Eli Lilly Cuts Price of Popular Weight-Loss Drug on Its Site — One Month After Trump Deal

Eli Lilly just slashed the price of its blockbuster weight-loss drug on its own website. The move comes exactly one month after the company inked a high-profile deal with former President Donald Trump—timing that’s raising more than a few eyebrows.

Direct-to-consumer price cut

This isn't a broad pharmacy markup adjustment. Lilly bypassed the traditional supply chain entirely and cut the price directly on its branded site. Patients can now access the medication for less—if they know where to look.

The Trump deal factor

The price trim lands precisely 30 days after Lilly and Trump finalized their agreement. While the company cites 'improved manufacturing efficiencies,' the calendar coincidence is a masterclass in political optics—and perhaps a preemptive shield against pricing criticism.

A new pharma playbook

Lilly’s maneuver signals a shift. Drugmakers are going direct, controlling the narrative and the price tag simultaneously. It’s a sleek, modern pivot that makes the old rebate-and-negotiation dance look downright archaic.

Wall Street’s cynical shrug

The finance crowd is watching with a mix of admiration and skepticism. Cutting your own website price is a brilliant PR move, but in the grand scheme of quarterly earnings, it’s often just a rounding error—a cost of doing business in the era of viral public scrutiny. The real money, as always, remains in the volume flowing through the legacy channels they’d never dare disrupt.

Key Takeaways

• Eli Lilly said Monday it is reducing the price of its Zepbound weight-loss drug on its platform LillyDirect.
• The move comes about a month after the company announced a deal with the Trump administration to lower weight-loss drug costs.

Eli Lilly (LLY) said Monday that it's lowering the price of its popular weight-loss drug Zepbound, about a month after striking a deal with the TRUMP administration to lower drug costs.

The company said the price for a once-a-month single vial purchased through its LillyDirect digital health care platform will go down $50 for the 2.5-, 7.5-, 10-, 12.5-, and 15-milligram doses, and $100 for the 5-milligram dose. The prices range from $299 for the lowest dose to $449 for the highest.

Why This News Is Significant

Lilly’s decision to lower Zepbound pricing comes amid growing political pressure on the company to make its weight-loss drugs more affordable.

The move follows a WHITE House meeting in November, where the president and Lilly CEO David Ricks announced plans to make the company's weight-loss drugs more affordable and accessible.

As part of that deal, Lilly will make Zepbound and obesity pill orforglipron available for no more than $50 a month for Medicare recipients starting next April, pending Food and Drug Administration approval.

In addition, the company agreed that for new medicines, it WOULD take “a more balanced pricing approach across developed nations.”  The Trump administration agreed to give Lilly three years of relief from tariffs, and it will not be subject to future pricing mandates.

Shares of Eli Lilly slid about 2% amid broader market losses Monday, after hitting an all-time high last week. They've added over a third of their value in 2025.

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