Quantum Leap: Top 5 Quantum Computing Stocks to Dominate November 2025

Wall Street's betting big on qubits—here's where the smart money's flowing as quantum goes mainstream.

The Quantum Gold Rush

Forget crypto—quantum computing's where the real volatility (and opportunity) lives now. These stocks aren't just riding the hype cycle—they're building the hardware rewriting the rules of finance, logistics, and cybersecurity.

1. The Blue-Chip Backbone

IBM and Google parent Alphabet keep dumping billions into quantum supremacy races. Their cloud-based quantum services already count 80% of Fortune 500 firms as clients—whether those clients understand the tech or not.

2. The Dark Horse

Startup Rigetti just scored a classified Pentagon contract. Their hybrid quantum-classical chips could be the bridge tech this industry desperately needs—if they don't burn through cash first.

3. The Supply Chain Play

Applied Materials doesn't make qubits—it sells the $4 million cryogenic systems that keep them from melting down. Like selling picks in a gold rush, but with better margins.

Quantum or Quagmire?

Analysts project 300% sector growth by 2030... assuming half these companies don't collapse under their own R&D budgets first. Remember—for every Amazon Web Services, there's a dozen Webvan flameouts.

TLDR

• IonQ stock has gained more than 600% over the past three years, leading quantum computing companies in market capitalization
• The company’s Q3 revenue jumped 222% year over year to $40 million, beating analyst expectations
• IonQ partnered with AstraZeneca, Nvidia, and Amazon to demonstrate quantum computing can speed up drug development by 20 times
• Management plans to scale the quantum system to 80,000 logical qubits by 2030
• Competitors Rigetti Computing and D-Wave Quantum have seen shares rise 156% and 293% respectively in 2025

IonQ has emerged as the market leader among quantum computing stocks after three years of strong performance. The company’s shares have climbed more than 600% during this period, giving it the highest market value among pure-play quantum computing firms.

IonQ, Inc., IONQ

The Maryland-based company reported third quarter revenue of $40 million in 2025. This represented a 222% increase compared to the same period one year earlier. The results exceeded Wall Street expectations for the quarter.

IonQ has spent over 30 years developing quantum computing technology. The company now competes with other public quantum firms including Rigetti Computing and D-Wave Quantum. Both rivals have also seen their stock prices rise sharply in 2025.

Rigetti Computing shares gained 156% through November 2025. The company operates its own chip fabrication facility in Fremont, California. This vertical integration gives Rigetti control over its supply chain as it develops quantum technology.

D-Wave Quantum posted even larger gains of 293% in 2025. The company focuses on quantum annealing, a specific type of quantum computing designed for optimization problems. D-Wave reported second quarter revenue of $3.1 million, up 42% year over year.

D-Wave Quantum Inc., QBTS

Strategic Partnerships Drive Growth

IonQ has formed partnerships with several major technology companies. These include deals with AstraZeneca, Nvidia, and Amazon. Earlier in 2025, these partners demonstrated how IonQ’s quantum computer could accelerate drug development processes.

The research showed quantum computing could complete a key drug development step 20 times faster than traditional methods. Tasks that typically take months could be reduced to just days. This application demonstrates potential real-world uses for the technology.

The company has also built relationships with firms in healthcare, semiconductors, and cloud services. These partnerships help validate IonQ’s technology and provide revenue opportunities. The company holds a portfolio of patents related to quantum computing.

Technology and Market Outlook

Quantum computers use qubits instead of traditional bits to perform calculations. Qubits can exist in multiple states at once, allowing quantum systems to solve certain complex problems faster than conventional supercomputers. The technology remains in early development stages.

IonQ management has set a goal to reach 80,000 logical qubits by 2030. This target aims to keep the company ahead of competitors in processing power. The quantum computing market could reach $1 trillion in value by 2035 according to a McKinsey forecast.

Alphabet’s Google believes commercially viable quantum computing applications could arrive within five years. However, mainstream adoption may take several decades longer. Companies are investing in the technology despite the uncertain timeline.

Rigetti received an $8.6 million grant from the Defense Advanced Research Projects Agency in 2020. Government support for quantum computing continues as nations view the technology as strategically important. The WHITE House denied plans to purchase stakes in quantum companies in October 2025.

Financial Performance and Valuations

All three major quantum computing stocks trade at high valuations relative to their current revenue. Rigetti trades at 1,110 times sales while D-Wave trades at 335 times sales. These multiples reflect investor expectations for future growth rather than current profitability.

Both Rigetti and D-Wave report operating losses as they spend heavily on research and development. D-Wave posted operating losses of $26.5 million in its most recent quarter. The path to profitability remains unclear for companies in this sector.

IonQ’s recent stock performance includes a steep pullback from recent highs. The quantum computing sector experiences high volatility as investors react to technology developments and market sentiment. Share prices can swing dramatically in short periods.