3 DeFi Protocols Poised to Dominate the $34T Stablecoin Boom in 2025, According to Arthur Hayes
- The $34 Trillion Stablecoin Opportunity
- The DeFi Protocols Positioned to Win
- The Regulatory Wildcard
- Q&A: Understanding the Stablecoin Revolution
The $34 Trillion Stablecoin Opportunity
Let's cut to the chase – stablecoins aren't just changing crypto, they're rewriting the rules of global finance. What started as a niche tool for crypto traders has exploded into what Ripple's Brad Garlinghouse predicts will become a $2 trillion market. But former BitMEX CEO Arthur Hayes just dropped a bombshell: he sees this ballooning to $34 trillion as non-US banks lose their Treasury Department safety net.
"The BRICS nations plus what I call 'Euro-poor' countries represent about $34 trillion in deposits that could flee traditional banking," Hayes explains in his characteristically blunt style. "When people realize their banks aren't backed by the full faith of the US Treasury? That's when stablecoins become the lifeboat."
The DeFi Protocols Positioned to Win
In this potential financial earthquake, three DeFi protocols have caught Hayes' eye as primary beneficiaries:
1. Ethena (ENA) – The Yield Machine
Ethena's USDe isn't your grandma's stablecoin. This synthetic dollar protocol combines delta hedging with staking rewards to deliver yields that make traditional savings accounts look pathetic. Hayes predicts USDe could capture over 25% of the stablecoin market, surpassing Circle's USDC. "When people discover they can earn 15% on dollar equivalents while their local currency inflates at 20%? That's financial survival," notes our BTCC market analyst.
2. Hyperliquid (HYPE) – The Binance Challenger
This perpetual swaps DEX has been quietly eating Binance's lunch with its minimal fees and on-chain transparency. "Hyperliquid could become the largest crypto exchange – period – by the end of this bull cycle," Hayes boldly claims. Recent TradingView data shows its daily volume growing 47% month-over-month while CEX volumes stagnate.
3. Ether.fi (ETHFI) – The Payments Play
Their Ether.fi Cash cards solve crypto's last-mile problem: spending digital dollars at your local coffee shop. "This might be the most important offline crypto payment solution of the decade," Hayes argues. The protocol's recent partnership with Visa (confirmed August 2025) suggests he might be right.

Hayes observes, highlighting why he believes these protocols will thrive as traditional finance falters.
The Regulatory Wildcard
Before you mortgage your house to buy ENA tokens, remember the elephant in the room: regulation. The US Treasury's recent "Operation Chokepoint 2.0" proposals could throw SAND in DeFi's gears. Our BTCC research team notes that stablecoin legislation remains the biggest unanswered question of 2025.
Always do your own research before investing in volatile crypto assets.
Q&A: Understanding the Stablecoin Revolution
Why does Arthur Hayes think $34T could flow into stablecoins?
Hayes believes non-US dollar deposits will seek alternatives as confidence in traditional banking erodes, particularly in BRICS and Eurozone countries facing currency instability.
What makes Ethena's USDe different from USDT or USDC?
USDe generates yield through sophisticated hedging strategies rather than relying solely on reserve assets, offering potentially higher returns in volatile markets.
How credible are Hayes' predictions about Hyperliquid surpassing Binance?
While ambitious, CoinMarketCap data shows DEXs collectively gained 210% market share since 2023. Hyperliquid's tech advantages make it a strong contender.