Semler Scientific Goes Full Crypto Whale—Now Holds 4,000+ Bitcoin

Another corporate balance sheet flips orange. Semler Scientific just crossed the 4,000 BTC threshold—joining the ranks of MicroStrategy and Tesla in betting big on digital gold.

Why? Maybe they read one too many ’hyperbitcoinization’ threads. Or maybe they’re tired of watching cash reserves rot at 0.5% interest while the Fed pretends inflation is ’transitory.’

Either way, their treasury strategy now looks more like a crypto hedge fund. Bold move for a medical tech firm—let’s see if shareholders cheer or bolt when the next 20% dip hits.

In Brief

• Semler Scientific acquired an additional 455 bitcoins for 50 million dollars between May 13 and 22, 2025.
• The company now holds 4,264 BTC with a market value of 474.4 million dollars.
• Its bitcoin yield reaches 25.8% since the beginning of the year, outperforming traditional markets.

A Strategic Purchase That Confirms the Trend

Semler Scientific has just reached a symbolic milestone in its bitcoin strategy. Between May 13 and 22, the Nasdaq-listed company spent 50 million dollars to acquire 455 additional bitcoins. The average purchase price is 109,801 dollars per unit, according to the 8-K filing published Friday.

This new acquisition raises Semler Scientific’s total holdings to 4,264 bitcoins. All of these assets, acquired for 390 million dollars, now have a market value exceeding 450 million dollars. A substantial gain demonstrating the relevance of this approach for the company specialized in early detection of chronic diseases.

The funding for this purchase comes from the $500 million At-The-Market (ATM) offering program launched last April. Semler Scientific issued 3,003,488 new shares, raising 114.8 million dollars to fund its bitcoin treasury. This financing method allows the company to increase its reserves without resorting to debt.

Semler Scientific’s “BTC yield,” now used as a key performance indicator by most companies adopting this strategy, stands at 25.8% in 2025.

This metric measures the evolution of the ratio between bitcoin holdings and the number of shares outstanding, providing investors with a clear vision of exposure per share.

The Stakes of a Profitable Bitcoin Strategy

Semler Scientific’s journey fits into a broader trend observed in financial markets. Like Strategy, many companies are adopting bitcoin as a strategic treasury reserve.

This approach fundamentally transforms their business model and value proposition for shareholders.

The company led by Eric Semler thus joins a select club of organizations betting on the long-term appreciation of bitcoin.

This strategy proves particularly attractive in a context of persistent inflation and accommodative monetary policies. Bitcoin acts as a natural hedge against the depreciation of fiat currencies.

However, this massive accumulation by companies raises important questions about the future of decentralization.

According to some experts, large companies could control up to 50% of bitcoins in circulation by 2045. This growing concentration could transform the very nature of the asset, originally designed as a decentralized monetary system.

The evolution of Semler Scientific’s stock price (SMLR) reflects this duality. Despite the success of its bitcoin strategy, the stock retreated by 6.7% to 41.89 dollars, with a market capitalization of 498 million dollars.

In short, Semler Scientific’s aggressive accumulation confirms bitcoin’s attractiveness for corporate treasuries. With a yield of 25.8% since the beginning of the year, this strategy is gradually transforming a medical device company into a crypto investment vehicle. This transformation perfectly illustrates the evolution of the modern financial landscape, where the boundaries between traditional sectors and digital assets are definitively blurring.

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