I'm trying to understand which drugs are subject to acute restrictions through the use of tethering. Can someone clarify this for me?
5 answers
Mon Jan 13 2025
This technology genetically engineers cells to express a unique protein known as the HaloTag Protein (HTP).
Mon Jan 13 2025
DART, or Drug Acutely Restricted by Tethering, represents a groundbreaking cell-specific technology.
Sun Jan 12 2025
The HaloTag Protein functions as a receptor, capable of binding to a specific chemical compound.
Sun Jan 12 2025
This chemical compound is referred to as the HaloTag Ligand (HTL), and it has the ability to attach to therapeutic drugs (Rx).
Sun Jan 12 2025
When introduced into the system, the HaloTag Ligand, with its attached drug, efficiently targets and binds to the HaloTag Protein expressed in the genetically modified cells.