I'm trying to understand the breakdown of MDS cases, specifically, I want to know what proportion of MDS cases are considered high-risk.
            
            
            
            
            
            
           
          
          
            5 answers
            
            
  
    
    Leonardo
    Wed Nov 20 2024
   
  
    A significant portion of MDS patients, estimated to be around 25-30%, are diagnosed with high-risk disease.
  
  
 
            
            
  
    
    CryptoVanguard
    Tue Nov 19 2024
   
  
    This high-risk MDS has the potential to evolve further, transitioning to secondary AML in approximately 30% of cases.
  
  
 
            
            
  
    
    Chiara
    Tue Nov 19 2024
   
  
    AML, as a progression of MDS, can lead to fatal outcomes in many patients.
  
  
 
            
            
  
    
    CryptoEmpireGuard
    Tue Nov 19 2024
   
  
    However, it is worth noting that mortality in MDS patients is not solely attributed to AML.
  
  
 
            
            
  
    
    Raffaele
    Tue Nov 19 2024
   
  
    In fact, bleeding and infections are also common causes of death in MDS patients, even without the development of AML.