I'm interested in understanding the binding location of STAT3. Could you please provide information on where STAT3 binds within the cell or to which molecules it specifically interacts with?
            
            
            
            
            
            
           
          
          
            5 answers
            
            
  
    
    KimchiQueenCharmingKissWarmth
    Wed Nov 06 2024
   
  
    Our research revealed that U-STAT3 molecules have the ability to bind to the GAS DNA-binding site.
  
  
 
            
            
  
    
    SeoulSerenitySeeker
    Wed Nov 06 2024
   
  
    This binding occurs in the form of dimers and monomers.
  
  
 
            
            
  
    
    Daniela
    Wed Nov 06 2024
   
  
    Furthermore, we discovered that U-STAT3 is also capable of binding to AT-rich DNA sequence sites.
  
  
 
            
            
  
    
    CryptoNerd
    Wed Nov 06 2024
   
  
    U-STAT3 demonstrates the ability to recognize specific DNA structures.
  
  
 
            
            
  
    
    CryptoMaven
    Tue Nov 05 2024
   
  
    These structures include 4-way junctions and DNA nodes, which are found within negatively supercoiled plasmid DNA.