How high is ace level in sarcoidosis?

In category I sarcoidosis, which typically involves the lungs and lymphatic system, a significant difference in serum ACE levels was observed between patients with the disease and those without. Specifically, the median serum ACE level among patients with category I sarcoidosis was 19.9 IU/L, with an interquartile range (IQR) of 15.3 to 31.7 IU/L.

Angiotensin-converting enzyme (ACE) levels have been studied extensively in patients with sarcoidosis, a multi-systemic granulomatous disorder. In this context, it is crucial to compare ACE levels between patients with different types of sarcoidosis and those without the disease.

In contrast, the median serum ACE level among individuals without sarcoidosis was notably lower, at 10.8 IU/L, with an IQR of 8.4 to 16.8 IU/L. This difference in ACE levels between the two groups was statistically significant, with a P-value of less than 0.01, indicating a strong association between elevated ACE levels and the presence of category I sarcoidosis.

It is important to note that ACE levels can vary depending on the type and severity of sarcoidosis. However, in category I, the elevation of ACE levels is often considered a useful diagnostic marker, as it can aid in distinguishing patients with sarcoidosis from those without the disease.

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