What is the first appearance of hand, foot, and mouth disease?

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The onset of fever, accompanied by a lack of appetite, a persistent runny nose, and a sore throat, can be indicative of a viral infection. These symptoms typically manifest between three to five days following exposure to the virus.

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Following the initial symptoms, an additional sign of the infection often presents itself in the form of a rash resembling blisters. This rash typically appears on the hands, feet, and inside the mouth, providing a further indication of the viral presence.

The blister-like rash develops as the virus progresses, usually occurring one to two days after the first set of symptoms have emerged. Its appearance serves as a crucial marker in the progression of the illness.