Is saying you're welcome condescending?

Could you elaborate on the notion that saying "you're welcome" could be perceived as condescending? I'm curious to understand the context in which this sentiment arises and how it might differ from a genuine expression of politeness or graciousness. Is there a specific tone or manner in which "you're welcome" is often delivered that could give it a negative connotation? Additionally, are there alternative phrases that might be more appropriate in certain situations to avoid any potential misinterpretation?