Who invented Ivacaftor?

Could you please elaborate on the origins of Ivacaftor and who was the individual or team responsible for its invention? I'm particularly curious to know if it was the result of a solo effort or a collaborative project, and if there were any key breakthroughs or challenges that led to its development. Additionally, I'm interested in knowing if the inventor or inventors had any prior experience in pharmaceutical research or a related field that may have contributed to their success in creating Ivacaftor.