What is the punishment for online gambling in the US?

I'm curious to know, what are the specific penalties imposed in the United States for engaging in online gambling activities? Do the laws vary by state, and are there any federal regulations in place that govern these offenses? Additionally, are there any exceptions or exemptions that apply to certain types of online gambling, such as those involving cryptocurrency transactions? It would be helpful to understand the full scope of the legal consequences associated with this type of activity.