What is Vertex Pharmaceuticals famous for?

Could you tell me what Vertex Pharmaceuticals is particularly renowned for in the pharmaceutical industry? Are they known for developing groundbreaking treatments for rare diseases, or are they perhaps at the forefront of drug discovery research? Do they have a reputation for innovative drug delivery systems, or is it their commitment to patient advocacy that sets them apart? I'm curious to understand what precisely Vertex Pharmaceuticals is famous for within the broader healthcare landscape.