What is 4E in science?

Excuse me, could you please clarify what you mean by "4E in science"? Is this referring to a specific concept, theory, or terminology used within the scientific community? If so, could you provide some context or additional information to help me understand the question better? Without further details, it's difficult for me to give an accurate answer as the term "4E" does not immediately correspond to a widely recognized concept in science. Perhaps you could elaborate on the context in which this term was mentioned or provide any relevant details that could assist in identifying its meaning.