Why did Hopper's wife leave him?

Can you provide some insight into the reasoning behind Hopper's wife's decision to leave him? Was there a specific event or series of events that led to this outcome? Or was it a gradual erosion of their relationship over time? What are the potential factors that may have contributed to this decision, and how might they have influenced her feelings towards Hopper? Additionally, how has this situation impacted Hopper personally and professionally, and what steps has he taken to move forward since her departure?