What are the disadvantages of persistence?

When it comes to the concept of persistence, it's often celebrated as a virtue that can lead to success and achievement. However, are there any potential drawbacks or disadvantages to this trait? Could it potentially lead to stubbornness or a refusal to adapt to changing circumstances? Is there a risk of becoming overly focused on a single goal to the detriment of other important aspects of life? Additionally, could the relentless pursuit of a goal lead to burnout or decreased motivation over time? These are just a few questions that come to mind when considering the potential disadvantages of persistence.