What are the disadvantages of MEV?

As a keen observer of the cryptocurrency space, I'm curious to understand the potential drawbacks of Miner Extractable Value, or MEV. Could you elaborate on the disadvantages that come with this phenomenon? How does it impact the fairness and security of decentralized networks, and what measures can be taken to mitigate these negative effects? Additionally, how does MEV contribute to the growing concerns around centralized power and influence within blockchain ecosystems?