What salary do you need to live comfortably in Boston?

I'm curious, what would you say is the salary required to live comfortably in Boston? With the city's high cost of living, including housing, transportation, and other essentials, it's important to have a clear understanding of the financial needs to maintain a decent standard of living. Could you elaborate on what factors contribute to determining this salary, and how one might go about estimating their personal financial requirements in Boston?