Does nicotine raise blood pressure?

Could you elaborate on the potential impact of nicotine on blood pressure? Specifically, is there scientific evidence to support the claim that nicotine consumption leads to an increase in blood pressure levels? If so, what are the mechanisms behind this effect and how significant is the increase typically observed? Additionally, are there any factors that may modulate the effect of nicotine on blood pressure, such as individual genetic differences or concurrent use of other substances?