Are nicotine pouches safer than chewing tobacco?

Could you elaborate on the potential safety benefits of nicotine pouches compared to chewing tobacco? Are there any scientific studies that have specifically compared the two in terms of their health risks? Are there any long-term effects of using nicotine pouches that consumers should be aware of? Additionally, what are the main ingredients in nicotine pouches and how do they differ from those found in chewing tobacco? Lastly, are there any recommended guidelines for the SAFE and responsible use of nicotine pouches?