What are the long term effects of kava?

What are the potential long-term consequences of consuming KAVA on a regular basis? Are there any negative health impacts that could arise from prolonged usage? Is there any research available that explores the long-term effects of kava on various aspects of health, such as mental health, physical health, and cognitive function? Additionally, what factors might contribute to the severity of these effects, such as dosage, frequency of use, and individual physiology?