Is Ledger safe to use?

I'm considering using Ledger to secure my cryptocurrency holdings, but I want to be sure it's a safe and reliable option. Can you tell me more about Ledger's security features and how it protects against potential threats? Are there any known vulnerabilities or security breaches that have occurred with Ledger wallets in the past? How does Ledger compare to other hardware wallets in terms of security and user-friendliness? And finally, are there any best practices I should follow to ensure the safety of my cryptocurrency when using Ledger?