Is running node profitable?

Could you please elaborate on the profitability of running a cryptocurrency node? Are there any tangible benefits or income streams associated with maintaining a node, or is it primarily a matter of contributing to the network's decentralization and security? Are there any costs involved that need to be considered when weighing the potential profitability of running a node? And, ultimately, are there any best practices or strategies for maximizing the potential profitability of a node, if any exist?