What destroys the ozone layer?

Could you elaborate on the key factors that contribute to the destruction of the ozone layer? I'm particularly interested in understanding the role of human activities and the specific chemicals involved. Are there any natural processes that also contribute to ozone depletion? Additionally, how does the ozone layer's destruction impact our environment and ecosystems? Could you provide some examples of the potential consequences? Lastly, are there any current initiatives or measures being taken to protect and restore the ozone layer? Thank you for your insights.