What is the difference between rune and THORChain?

Could you please elaborate on the distinctions between Rune and THORChain? I'm particularly interested in understanding how they differ in terms of their functionalities, use cases, and the underlying technologies that they are built upon. Additionally, I would appreciate it if you could highlight any notable advantages or disadvantages of each, as well as their respective positions in the broader cryptocurrency and finance landscape. Thank you for your assistance in clarifying these points.