Can ETF become zero?

Could you please elaborate on the possibility of an Exchange-Traded Fund (ETF) reaching a value of zero? Could such a scenario arise due to market fluctuations, operational issues, or other factors? How might investors react to such a situation, and what strategies could they employ to mitigate potential losses? Furthermore, what measures are typically taken by regulatory bodies to safeguard investors in case of such extreme events? I'm interested in understanding the underlying mechanisms and considerations that could lead to this unprecedented outcome.