What are the disadvantages of kava?

Could you please elaborate on the potential drawbacks of Kava? I'm particularly interested in understanding its negative effects on health, if any, as well as any potential risks or limitations in its usage. Additionally, could you discuss any challenges or issues that might arise when incorporating Kava into a financial or investment portfolio? I'm seeking a comprehensive overview of its disadvantages to make an informed decision about its suitability for my needs. Thank you in advance for your assistance.