What are 10 disadvantages of GMOs?

Could you please elaborate on the ten drawbacks associated with Genetically Modified Organisms? I'm particularly interested in understanding the potential health risks, ecological impacts, and the economic considerations surrounding the utilization of GMOs. Additionally, I'm curious about any potential long-term consequences and the sustainability issues that might arise from their widespread use. Could you also discuss any ethical concerns or public perception challenges that are often associated with GMOs? Thank you for your detailed response.